Pumps used in high-pressure chromatography
Pumps used in high-pressure chromatography such as HPLC and ion chromatography are much like small piston metering pumps.
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For wear resistance and chemical resistance to solvents, etc., typically the pistons are made of artificial sapphire and the ball check valves have ruby balls and sapphire seats.
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To produce good chromatograms, it is desirable to have a pumping flow rate as constant as possible. Either a single piston pump with a quick refill is used or a double pump head with coordinated piston strokes is used to provide as constant a pumping rate as possible.
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Diaphragm and peristaltic pumps
In order to avoid leakage at the packing or seal particularly when a liquid is dangerous, toxic, or noxious, diaphragm pumps are used for metering.
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Diaphragm pumps have a diaphragm through which repeated compression/decompression motion is transmitted.
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The liquid does not penetrate through the diaphragm, so the liquid inside the pump is sealed off from the outside. dosing and injection system. Such motion changes the volume of a chamber in the pump head so that liquid enters through an inlet check valve during decompression and exits through an outlet check valve during compression, in a manner similar to piston pumps. Diaphragm pumps can also be made which discharge at fairly high pressure. Diaphragm metering pumps are commonly hydraulically driven.
Peristaltic pumps use motor-driven rollers to roll along flexible tubing, compressing it to push forward a liquid inside. dosing and injection system. Although peristaltic pumps can be used to meter at lower pressures, the flexible tubing is limited in the level of pressure it can withstand.
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